Ndufa8 conditional Knockout mouse

Target

Gene symbol :

Ndufa8

NCBI gene ID :

68375

Gene full name :

NADH:ubiquinone oxidoreductase subunit A8

Synonym :

CI-B12

Protein function

Protein name :

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8

Accessory subunit of mitochondrial Complex I; contributes to respiratory chain assembly and stability

Expected phenotype

Limited mouse data; potential role in mitochondrial dysfunction

Human disease relevance

Implicated in mitochondrial disorders; mutations can affect oxidative metabolism

Model applications

Potential model for respiratory chain deficiencies and mitochondrial pathologies

Keywords:

Mitochondria, Complex I, Respiratory chain, Metabolic disorders

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ndufa8

conditional Knockout mouse

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