Nedd4 conditional Knockout mouse

Target

Gene symbol :

Nedd4

NCBI gene ID :

17999

Gene full name :

Neural precursor cell expressed, developmentally down-regulated 4

Synonym :

Nedd4-1, Nedd4a, E430025J12Rik

Protein function

Protein name :

NEDD4

E3 ubiquitin-protein ligase; regulates protein degradation.

Expected phenotype

Abnormal neuronal development; impaired axon growth.

Human disease relevance

Linked to Liddle syndrome and Charcot-Marie-Tooth disease.

Model applications

Research on protein ubiquitination and neuronal development.

Keywords:

Ubiquitin ligase, Protein degradation, Neurodevelopment

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Nedd4

conditional Knockout mouse

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