Nedd4 conditional Knockout mouse

Target

Gene symbol :

Nedd4

NCBI gene ID :

17999

Gene full name :

Neural precursor cell expressed, developmentally down-regulated 4

Synonym :

Nedd4-1, Nedd4a, E430025J12Rik

Protein function

Protein name :

NEDD4

E3 ubiquitin-protein ligase; regulates protein degradation.

Expected phenotype

Abnormal neuronal development; impaired axon growth.

Human disease relevance

Linked to Liddle syndrome and Charcot-Marie-Tooth disease.

Model applications

Research on protein ubiquitination and neuronal development.

Keywords:

Ubiquitin ligase, Protein degradation, Neurodevelopment

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Nedd4

conditional Knockout mouse

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hPD-1 hLAG3

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hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.

hPD-1 hLAG3

Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur.