Nedd4 conditional Knockout mouse

Target

Gene symbol :

Nedd4

NCBI gene ID :

17999

Gene full name :

Neural precursor cell expressed, developmentally down-regulated 4

Synonym :

Nedd4-1, Nedd4a, E430025J12Rik

Protein function

Protein name :

NEDD4

E3 ubiquitin-protein ligase; regulates protein degradation.

Expected phenotype

Abnormal neuronal development; impaired axon growth.

Human disease relevance

Linked to Liddle syndrome and Charcot-Marie-Tooth disease.

Model applications

Research on protein ubiquitination and neuronal development.

Keywords:

Ubiquitin ligase, Protein degradation, Neurodevelopment

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Nedd4

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe