Pex10 conditional Knockout mouse

Target

Gene symbol :

Pex10

NCBI gene ID :

668173

Gene full name :

Peroxisomal biogenesis factor 10

Synonym :

—

Protein function

Protein name :

Peroxisomal membrane protein PEX10

E3 ubiquitin ligase required for peroxisome assembly and matrix protein import

Expected phenotype

Defective peroxisome biogenesis; embryonic lethality in knockout mice

Human disease relevance

Mutations cause Zellweger spectrum disorders in humans

Model applications

Model for peroxisome biogenesis and metabolic disorders

Keywords:

Peroxisome, Organelle biogenesis, Zellweger, Ubiquitin ligase

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pex10

conditional Knockout mouse

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