Polr3f conditional Knockout mouse

Target

Gene symbol :

Polr3f

NCBI gene ID :

70408

Gene full name :

RNA polymerase III subunit F

Synonym :

RPC6

Protein function

Protein name :

DNA-directed RNA polymerase III subunit RPC6

Subunit of RNA Pol III complex; transcribes small RNAs like tRNAs and 5S rRNA

Expected phenotype

No overt phenotype in mouse models reported

Human disease relevance

Mutations linked to hypomyelinating leukodystrophies

Model applications

Studied in tRNA synthesis and RNA Pol III-related diseases

Keywords:

RNA polymerase III, tRNA, Transcription, Leukodystrophy

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Polr3f

conditional Knockout mouse

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Easy access to models

Models with certified health status from professional breeders in US and Europe