Psmc2 conditional Knockout mouse

Target

Gene symbol :

Psmc2

NCBI gene ID :

19181

Gene full name :

26S proteasome regulatory subunit 7

Synonym :

Mss1

Protein function

Protein name :

PSMC2

ATPase within the 19S regulatory cap of the proteasome

Expected phenotype

Defective proteasome activity, protein homeostasis issues

Human disease relevance

Implicated in melanoma, cystic fibrosis

Model applications

Models for proteostasis and cancer

Keywords:

Proteasome, Protein degradation, ATPase

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Psmc2

conditional Knockout mouse

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