Target

Gene symbol :  
Ptges2
NCBI gene ID :  
96979
Gene full name :  
Prostaglandin E synthase 2
Synonym :  
p53N10, mPGE synthase-2

Protein function

Protein name :  
Microsomal prostaglandin E synthase-2
Enzyme converting PGH₂ to PGE₂; regulates inflammatory responses and cell survival

Expected phenotype

Knockouts show impaired PGE₂ synthesis and altered immune responses

Human disease relevance

Linked to inflammation, cancer, and immune disorders

Model applications

Studied in prostaglandin signaling and inflammation models

Keywords:

Prostaglandin, Inflammation, Lipid metabolism, PGE₂

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Ptges2

conditional Knockout mouse

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