Rfxank conditional Knockout mouse

Target

Gene symbol :

Rfxank

NCBI gene ID :

19727

Gene full name :

Regulatory factor X-associated ankyrin-containing protein

Synonym :

RFX-BP

Protein function

Protein name :

RFXANK

Required for MHC class II gene expression in antigen-presenting cells.

Expected phenotype

Impaired MHC II expression, compromised immunity

Human disease relevance

Linked to bare lymphocyte syndrome (immunodeficiency)

Model applications

Immunology, antigen presentation models

Keywords:

Transcription factor, Immune regulation, MHC II

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Rfxank

conditional Knockout mouse

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