Supv3l1 conditional Knockout mouse

Target

Gene symbol :

Supv3l1

NCBI gene ID :

338359

Gene full name :

SUV3-like RNA helicase (S. cerevisiae)

Synonym :

SUV3, Mtr4

Protein function

Protein name :

ATP-dependent RNA helicase SUPV3L1

RNA helicase involved in mitochondrial RNA degradation and processing

Expected phenotype

KO mice show embryonic lethality and mitochondrial dysfunction

Human disease relevance

Linked to mitochondrial disease pathways

Model applications

Model for mitochondrial RNA metabolism and helicase function

Keywords:

RNA helicase, Mitochondria, RNA processing, SUV3

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Supv3l1

conditional Knockout mouse

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