Target

Gene symbol :  
Usp19
NCBI gene ID :  
71472
Gene full name :  
Ubiquitin specific peptidase 19
Synonym :  
Usp17l

Protein function

Protein name :  
Ubiquitin carboxyl-terminal hydrolase 19
Deubiquitinase involved in protein homeostasis, cell cycle regulation, and ER-associated degradation

Expected phenotype

Knockout mice show reduced muscle mass and impaired differentiation

Human disease relevance

Implicated in cancer, muscle wasting, and immune regulation

Model applications

Used in studies of protein turnover, myogenesis, and cancer

Keywords:

Ubiquitin, Deubiquitinase, ERAD, Muscle, Cell cycle

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Usp19

conditional Knockout mouse

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