Vdac1 conditional Knockout mouse

Target

Gene symbol :

Vdac1

NCBI gene ID :

22333

Gene full name :

Voltage-dependent anion channel 1

Synonym :

VDAC-1, Vdac, mVDAC1

Protein function

Protein name :

Voltage-dependent anion-selective channel protein 1

Forms channels in the outer mitochondrial membrane allowing transport of ATP, ADP, and other metabolites; key in apoptosis and energy metabolism

Expected phenotype

Altered mitochondrial function, increased resistance to apoptosis

Human disease relevance

Implicated in cancer, neurodegeneration (e.g., Alzheimer’s), and metabolic diseases

Model applications

Used in studies of apoptosis, mitochondrial physiology, and drug targeting

Keywords:

Mitochondria, Apoptosis, Metabolism, Transport

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Vdac1

conditional Knockout mouse

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