Target

Gene symbol :  
Xxylt1
NCBI gene ID :  
268880
Gene full name :  
Xyloside xylosyltransferase 1
Synonym :  
Xyxlt, XylT-Like

Protein function

Protein name :  
Xyloside xylosyltransferase 1
Involved in glycosylation of Notch EGF repeats

Expected phenotype

Disruption affects Notch signaling pathway

Human disease relevance

Linked to congenital disorders of glycosylation

Model applications

Model for Notch pathway and glycosylation defects

Keywords:

Notch signaling, Glycosylation, Xylosyltransferase, EGF modification

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Xxylt1

conditional Knockout mouse

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