Target

Gene symbol :  
Zfyve28
NCBI gene ID :  
231125
Gene full name :  
Zinc finger FYVE-type containing 28
Synonym :  
Lst2

Protein function

Protein name :  
FYVE-type zinc finger domain-containing protein 28
Involved in EGFR endocytosis and lysosomal targeting

Expected phenotype

Limited phenotype data

Human disease relevance

Implicated in tumor suppression and EGFR signaling regulation

Model applications

Studied in EGFR degradation and receptor trafficking

Keywords:

FYVE domain, EGFR signaling, Endocytosis, Lysosome

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Zfyve28

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe