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genOway’s presentation at the PEGS Europe, Lisbon 2026

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Tuesday, November 17, 2026, 10:00-10:30 am

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Track: C4B: T cell engagers

Presenter: Kader Thiam, CSO & SVP – Discovery, Preclinical Models & Services

Title: "BRGSF-HIS: A Humanized Platform for Efficacy and Safety Evaluation of T Cell Engagers​"

• Outlining genO-BRGSF-HIS mice: a CD34⁺-reconstituted model with functional human lymphoid and myeloid compartments, without side effects
• Evidencing the recruitment of human immune cells to tumor microenvironment, as well as their activation status
• Highlighting the key role of myeloid compartment in the translatable assessment of biologic's safety in humanized models

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We look forwards seeing you there!