Notch1 conditional Knockout mouse

Target

Gene symbol :

Notch1

NCBI gene ID :

18128

Gene full name :

Notch 1

Synonym :

Notch homolog 1

Protein function

Protein name :

Notch1

Transmembrane receptor involved in cell fate decisions.

Expected phenotype

Abnormal cell differentiation; increased tumorigenesis.

Human disease relevance

Implicated in T-cell acute lymphoblastic leukemia and other cancers.

Model applications

Research on cell differentiation and oncogenesis.

Keywords:

Notch signaling, Cell fate determination, Cancer

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
WoldWide delivery by professional breeders

Notch1

conditional Knockout mouse

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