ROSA26-Dre mouse line

Dre recombinase driver line for ubiquitous recombination at Rox sites

Availability & Delivery:

• Cryo-recovery using in-house SOPF facilities • Worldwide delivery by professional breeders

Specifications

Expression driver gene:
Gt(ROSA)26Sor
Target system:
Ubiquitous
Genetic background:
C57BL/6N
Cre type:
Dre recombinase
Reporter:
None
Induction method:
Constitutive
MGI ID:
MGI:6335542

Scientific relevance & applications  

The ROSA26 locus is widely used for ubiquitous and stable gene expression across tissues. This ROSA26-Dre mouse line expresses Dre recombinase, which recognizes Rox sites and enables site-specific recombination independent of the Cre/loxP system. It is particularly valuable for intersectional genetics approaches when combined with Cre lines, allowing dual recombinase strategies for precise spatial and temporal control of gene manipulation.

ROSA26-Dre mouse line

mouse line

Get in touch about

Let us know how we can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe