Target

Gene symbol :  
Alox8
NCBI gene ID :  
11688
Gene full name :  
Arachidonate 8-lipoxygenase
Synonym :  
Arachidonate 8-lipoxygenase

Protein function

Protein name :  
ALOX8
Catalyzes the dioxygenation of PUFAs, regulating lipid mediator production.

Expected phenotype

Inflammation sensitivity, altered lipid metabolism

Human disease relevance

Implicated in immune and barrier function

Model applications

Inflammation, lipid metabolism

Keywords:

Lipoxygenase, Eicosanoids, Inflammatory response

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Alox8

conditional Knockout mouse

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