Target

Gene symbol :  
Bag3
NCBI gene ID :  
29810
Gene full name :  
Bcl2-associated athanogene 3
Synonym :  
BCL2-associated athanogene 3

Protein function

Protein name :  
BAG3
Co-chaperone regulating autophagy, apoptosis, and cytoskeleton.

Expected phenotype

Muscle degeneration, cardiac defects

Human disease relevance

Linked to myofibrillar myopathy and cardiomyopathy

Model applications

Muscle biology, stress response

Keywords:

Autophagy, Myopathy, Apoptosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Bag3

conditional Knockout mouse

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