Target

Gene symbol :  
Cd22
NCBI gene ID :  
12483
Gene full name :  
CD22 molecule
Synonym :  
Siglec-2

Protein function

Protein name :  
CD22
B-cell specific surface molecule that regulates BCR signaling.

Expected phenotype

Hyperactive B cells

Human disease relevance

Target in B-cell malignancies and autoimmunity

Model applications

B-cell immunology, lymphoma research

Keywords:

Siglec, BCR signaling, Autoimmune

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Cd22

conditional Knockout mouse

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