Target

Gene symbol :  
Col4a3
NCBI gene ID :  
12828
Gene full name :  
Collagen type IV alpha 3 chain
Synonym :  
Collagen type IV alpha 3

Protein function

Protein name :  
COL4A3
Basement membrane protein critical for kidney glomerular filtration.

Expected phenotype

Glomerular defects, hematuria

Human disease relevance

Mutations cause Alport syndrome

Model applications

Kidney filtration, basement membrane

Keywords:

Collagen IV, Alport syndrome, ECM

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Col4a3

conditional Knockout mouse

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