Col4a3 conditional Knockout mouse

Target

Gene symbol :

Col4a3

NCBI gene ID :

12828

Gene full name :

Collagen type IV alpha 3 chain

Synonym :

Collagen type IV alpha 3

Protein function

Protein name :

COL4A3

Basement membrane protein critical for kidney glomerular filtration.

Expected phenotype

Glomerular defects, hematuria

Human disease relevance

Mutations cause Alport syndrome

Model applications

Kidney filtration, basement membrane

Keywords:

Collagen IV, Alport syndrome, ECM

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Col4a3

conditional Knockout mouse

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