Ece1 conditional Knockout mouse

Target

Gene symbol :

Ece1

NCBI gene ID :

230857

Gene full name :

Endothelin converting enzyme 1

Synonym :

Endothelin converting enzyme 1

Protein function

Protein name :

ECE1

Converts inactive endothelin precursors to active peptides involved in vasoconstriction and development.

Expected phenotype

Cardiovascular and craniofacial anomalies

Human disease relevance

Linked to Hirschsprung disease and hypertension

Model applications

Cardiovascular biology, neural crest development

Keywords:

Endothelin, Vasoregulation, Neural crest

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ece1

conditional Knockout mouse

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