Target

Gene symbol :  
G3bp2
NCBI gene ID :  
23881
Gene full name :  
Ras GTPase-activating protein-binding protein 2
Synonym :  
Ras-GAP SH3 domain–binding protein 2, G3BP-B

Protein function

Protein name :  
G3BP2
RNA-binding protein involved in stress granule assembly and mRNA stabilization

Expected phenotype

Impaired stress response, altered RNA metabolism

Human disease relevance

Potential links to neurodegeneration and cancer progression

Model applications

Stress response and RNA biology models

Keywords:

Stress granules, RNA-binding, mRNA regulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

G3bp2

conditional Knockout mouse

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