Target

Gene symbol :  
Hells
NCBI gene ID :  
15201
Gene full name :  
Helicase, lymphoid specific
Synonym :  
Lsh, PASG, SMARCA6

Protein function

Protein name :  
HELLS
Chromatin remodeling ATPase involved in DNA methylation and gene silencing.

Expected phenotype

Developmental abnormalities, immune defects

Human disease relevance

Associated with immunodeficiency and cancer.

Model applications

Studies on DNA methylation, chromatin remodeling, and immune function.

Keywords:

Chromatin Remodeling, DNA Methylation, Immunodeficiency

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Hells

conditional Knockout mouse

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