Target

Gene symbol :  
Kcnb1
NCBI gene ID :  
16500
Gene full name :  
Potassium voltage-gated channel subfamily B member 1
Synonym :  
Kv2.1

Protein function

Protein name :  
Kv2.1
Delayed rectifier potassium channel involved in action potential repolarization in neurons.

Expected phenotype

Neurological deficits and altered neuronal excitability.

Human disease relevance

Associated with epileptic encephalopathy and neurodevelopmental disorders.

Model applications

Research on neuronal excitability and epilepsy.

Keywords:

Voltage-gated channel, Neuronal function, Epilepsy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Kcnb1

conditional Knockout mouse

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