Target

Gene symbol :  
Kit
NCBI gene ID :  
16590
Gene full name :  
KIT proto-oncogene, receptor tyrosine kinase
Synonym :  
CD117, SCFR

Protein function

Protein name :  
c-KIT
Regulates hematopoiesis, melanogenesis, and germ cell development.

Expected phenotype

Pigmentation defects, infertility, anemia

Human disease relevance

Target in mast cell tumors and GIST

Model applications

Stem cell biology, oncogenic signaling

Keywords:

Tyrosine kinase, Hematopoiesis, Pigmentation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Kit

conditional Knockout mouse

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