Kit conditional Knockout mouse

Target

Gene symbol :

Kit

NCBI gene ID :

16590

Gene full name :

KIT proto-oncogene, receptor tyrosine kinase

Synonym :

CD117, SCFR

Protein function

Protein name :

c-KIT

Regulates hematopoiesis, melanogenesis, and germ cell development.

Expected phenotype

Pigmentation defects, infertility, anemia

Human disease relevance

Target in mast cell tumors and GIST

Model applications

Stem cell biology, oncogenic signaling

Keywords:

Tyrosine kinase, Hematopoiesis, Pigmentation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Kit

conditional Knockout mouse

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