Target

Gene symbol :  
Krt74
NCBI gene ID :  
406222
Gene full name :  
Keratin 74
Synonym :  
Hha6, K6irs1

Protein function

Protein name :  
Keratin, type II cytoskeletal 74
Structural protein in hair follicles and inner root sheath

Expected phenotype

Abnormal hair shaft formation; hair loss in mutants

Human disease relevance

Mutations linked to hypotrichosis in humans

Model applications

Used in studies of hair development and skin disorders

Keywords:

Keratin, Hair follicle, Cytoskeleton, Hypotrichosis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Krt74

conditional Knockout mouse

Get in touch about

Let us know how can help
Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe