Notch3 conditional Knockout mouse

Target

Gene symbol :

Notch3

NCBI gene ID :

18131

Gene full name :

Notch receptor 3

Synonym :

-

Protein function

Protein name :

NOTCH3

Transmembrane receptor in cell fate decisions during vascular and neural development.

Expected phenotype

Vascular smooth muscle defects

Human disease relevance

Linked to CADASIL and vascular diseases

Model applications

Vascular development, neurovascular disease models

Keywords:

Notch signaling, Vasculature, CADASIL

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Notch3

conditional Knockout mouse

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