Target

Gene symbol :  
Notch3
NCBI gene ID :  
18131
Gene full name :  
Notch receptor 3
Synonym :  
-

Protein function

Protein name :  
NOTCH3
Transmembrane receptor in cell fate decisions during vascular and neural development.

Expected phenotype

Vascular smooth muscle defects

Human disease relevance

Linked to CADASIL and vascular diseases

Model applications

Vascular development, neurovascular disease models

Keywords:

Notch signaling, Vasculature, CADASIL

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Notch3

conditional Knockout mouse

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