Target

Gene symbol :  
Pd-1
NCBI gene ID :  
18566
Gene full name :  
Programmed cell death 1
Synonym :  
Pdcd1

Protein function

Protein name :  
PD-1
Immune checkpoint receptor inhibiting T-cell activity.

Expected phenotype

Enhanced immune responses, autoimmunity

Human disease relevance

Therapeutic target in cancer immunotherapy

Model applications

Immune checkpoint inhibition, T-cell exhaustion

Keywords:

PD-1, Checkpoint, Immunotherapy

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Pd-1

conditional Knockout mouse

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