Pfkfb3 conditional Knockout mouse

Target

Gene symbol :

Pfkfb3

NCBI gene ID :

170768

Gene full name :

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

Synonym :

iPfk2, Pfkfb-3

Protein function

Protein name :

PFKFB3

Bifunctional enzyme regulating glycolysis via fructose-2,6-bisphosphate levels

Expected phenotype

Knockouts impair glycolytic flux and immune responses

Human disease relevance

Associated with cancer metabolism and inflammation

Model applications

Studied in cancer, immunometabolism, and angiogenesis

Keywords:

Glycolysis, Warburg effect, Immunometabolism, PFKFB

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pfkfb3

conditional Knockout mouse

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