Pfkfb3 conditional Knockout mouse

Target

Gene symbol :

Pfkfb3

NCBI gene ID :

170768

Gene full name :

6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

Synonym :

iPfk2, Pfkfb-3

Protein function

Protein name :

PFKFB3

Bifunctional enzyme regulating glycolysis via fructose-2,6-bisphosphate levels

Expected phenotype

Knockouts impair glycolytic flux and immune responses

Human disease relevance

Associated with cancer metabolism and inflammation

Model applications

Studied in cancer, immunometabolism, and angiogenesis

Keywords:

Glycolysis, Warburg effect, Immunometabolism, PFKFB

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Pfkfb3

conditional Knockout mouse

Get in touch about

Let us know how we can help

Scientific excellence

From model design to experimental results
Featured in 600+ scientific articles

Collaborative approach

Collaboration with 17 Top Pharmas,
170+ Biotechs and 380+ Academic Institutions

Robust validation data on catalog models

Generated with biopharma partners and in-house

Innovative technologies

and guaranteed freedom to operate

Easy access to models

Models with certified health status from professional breeders in US and Europe