Target

Gene symbol :  
Plcg2
NCBI gene ID :  
234779
Gene full name :  
Phospholipase C gamma 2
Synonym :  
PLC-γ2

Protein function

Protein name :  
PLCγ2
Mediates immune receptor signaling in B cells and myeloid cells.

Expected phenotype

Defective immune activation

Human disease relevance

Linked to autoinflammation, B-cell malignancies

Model applications

BCR signaling, inflammation, innate immunity

Keywords:

PLCγ, Calcium signaling, B-cell

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Plcg2

conditional Knockout mouse

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