Target

Gene symbol :  
Plpp1
NCBI gene ID :  
19012
Gene full name :  
Phospholipid phosphatase 1
Synonym :  
Lpp1, Ppap2a

Protein function

Protein name :  
PLPP1
Dephosphorylates lipid signaling molecules like LPA and S1P.

Expected phenotype

Disrupted lipid signaling

Human disease relevance

Associated with cancer, vascular and metabolic disorders

Model applications

Lipid metabolism, inflammation

Keywords:

S1P, LPA, Lipid signaling

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Plpp1

conditional Knockout mouse

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