Psgl1 conditional Knockout mouse

Target

Gene symbol :

Psgl1

NCBI gene ID :

20345

Gene full name :

P-selectin glycoprotein ligand 1

Synonym :

Selplg, CD162

Protein function

Protein name :

PSGL-1

Mediates leukocyte rolling on activated endothelium via selectin binding.

Expected phenotype

Impaired leukocyte migration

Human disease relevance

Relevant in atherosclerosis and inflammatory diseases

Model applications

Leukocyte trafficking, inflammation

Keywords:

Selectins, Inflammation, Adhesion molecules

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Psgl1

conditional Knockout mouse

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