Target

Gene symbol :  
Psgl1
NCBI gene ID :  
20345
Gene full name :  
P-selectin glycoprotein ligand 1
Synonym :  
Selplg, CD162

Protein function

Protein name :  
PSGL-1
Mediates leukocyte rolling on activated endothelium via selectin binding.

Expected phenotype

Impaired leukocyte migration

Human disease relevance

Relevant in atherosclerosis and inflammatory diseases

Model applications

Leukocyte trafficking, inflammation

Keywords:

Selectins, Inflammation, Adhesion molecules

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Psgl1

conditional Knockout mouse

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