Target

Gene symbol :  
S1pr5
NCBI gene ID :  
94226
Gene full name :  
Sphingosine-1-phosphate receptor 5
Synonym :  
Edg8, S1P5, lpB4

Protein function

Protein name :  
S1P5 receptor
GPCR involved in lymphocyte trafficking and neurogenesis via S1P signaling.

Expected phenotype

Impaired immune cell migration and behavior

Human disease relevance

Linked to neurodegeneration, inflammation, and cancer

Model applications

Immune trafficking, neuroimmunology

Keywords:

GPCR, S1P, Inflammation, Lymphocyte

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

S1pr5

conditional Knockout mouse

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