Target

Gene symbol :  
Slc48a1
NCBI gene ID :  
67739
Gene full name :  
Solute carrier family 48 member 1
Synonym :  
HRG1

Protein function

Protein name :  
SLC48A1 (HRG1)
Transports heme out of lysosomes during erythrophagocytosis.

Expected phenotype

Impaired heme homeostasis

Human disease relevance

Linked to iron metabolism and anemia

Model applications

Erythrophagocytosis, iron recycling

Keywords:

Heme transporter, Macrophage, Iron

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Slc48a1

conditional Knockout mouse

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