Target

Gene symbol :  
Smad3
NCBI gene ID :  
17127
Gene full name :  
SMAD family member 3
Synonym :  
Madh3

Protein function

Protein name :  
SMAD3
Signal transducer for TGF-β pathway, regulating gene transcription and fibrosis.

Expected phenotype

Reduced fibrosis, altered immune response

Human disease relevance

Implicated in fibrosis, cancer, and autoimmune disorders

Model applications

Fibrosis, TGF-β signaling, immune regulation

Keywords:

TGF-β, Fibrosis, Immune modulation

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Smad3

conditional Knockout mouse

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