Target

Gene symbol :  
Uchl1
NCBI gene ID :  
22223
Gene full name :  
Ubiquitin carboxyl-terminal hydrolase L1
Synonym :  
PGP 9.5, PARK5, UCH-L1

Protein function

Protein name :  
UCHL1
Neuronal deubiquitinase critical for synaptic function

Expected phenotype

Neurodegeneration, impaired motor and sensory function

Human disease relevance

Linked to Parkinson’s, Alzheimer’s, neuropsychiatric disorders

Model applications

Neurodegeneration and neuronal function models

Keywords:

Neuronal, DUB, Neurodegeneration

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Uchl1

conditional Knockout mouse

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Models with certified health status from professional breeders in US and Europe