Wars conditional Knockout mouse

Target

Gene symbol :

Wars

NCBI gene ID :

22375

Gene full name :

Tryptophanyl-tRNA synthetase

Synonym :

WRS, WARS1

Protein function

Protein name :

WARS

Catalyzes aminoacylation of tRNA^Trp; also involved in angiogenesis and immune regulation

Expected phenotype

Embryonic lethality, vascular defects

Human disease relevance

Implicated in interstitial lung disease, neuropathy

Model applications

Translation and angiogenesis models

Keywords:

Aminoacyl-tRNA synthetase, Angiogenesis, Translation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Wars

conditional Knockout mouse

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