Target

Gene symbol :  
Zeb1
NCBI gene ID :  
21417
Gene full name :  
Zinc finger E-box-binding homeobox 1
Synonym :  
TCF8, δEF1

Protein function

Protein name :  
ZEB1
Transcriptional repressor that controls epithelial-to-mesenchymal transition (EMT).

Expected phenotype

Abnormal epithelial differentiation

Human disease relevance

Key role in cancer metastasis and fibrosis

Model applications

EMT modeling, cancer progression

Keywords:

EMT, Transcription factor, Metastasis

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Zeb1

conditional Knockout mouse

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