Adar conditional Knockout mouse

Target

Gene symbol :

Adar

NCBI gene ID :

56417

Gene full name :

Adenosine deaminase acting on RNA 1

Synonym :

ADAR1, DSRAD1, p150/p110

Protein function

Protein name :

ADAR

A-to-I RNA editing enzyme; modulates dsRNA sensing and transcript diversity

Expected phenotype

Embryonic lethality, autoimmunity

Human disease relevance

Mutations cause Aicardi–Goutières syndrome and dyschromatosis

Model applications

RNA editing and immune response models

Keywords:

RNA editing, A-to-I, Immune response

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Adar

conditional Knockout mouse

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