Target

Gene symbol :  
Arid2
NCBI gene ID :  
77044
Gene full name :  
AT‑rich interaction domain 2
Synonym :  
zipzap/p200, 1700124K17Rik, 4432409D24Rik

Protein function

Protein name :  
AT‑rich interactive domain‑containing protein 2
Subunit of PBAF chromatin remodeling complex; regulates transcription/DNA repair

Expected phenotype

Embryonic lethality, embryonic heart and liver defects

Human disease relevance

Associated with Coffin‑Siris syndrome and hepatocellular carcinoma

Model applications

Used in chromatin remodeling, development, and cancer biology

Keywords:

Chromatin, PBAF, Transcription, DNA repair

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arid2

conditional Knockout mouse

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