Target

Gene symbol :  
Arpc2
NCBI gene ID :  
76709
Gene full name :  
Actin related protein 2/3 complex subunit 2
Synonym :  
Arc34

Protein function

Protein name :  
Actin-related protein 2/3 complex subunit 2
Core subunit of Arp2/3 complex; essential for actin nucleation and cytoskeletal remodeling

Expected phenotype

Embryonic lethal when knocked out

Human disease relevance

Involved in cell motility, cancer invasion, immune synapse

Model applications

Used in cytoskeletal dynamics and actin polymerization studies

Keywords:

Actin, Cytoskeleton, Arp2/3, Cell motility

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Arpc2

conditional Knockout mouse

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