Cdsn conditional Knockout mouse

Target

Gene symbol :

Cdsn

NCBI gene ID :

386463

Gene full name :

Corneodesmosin

Synonym :

—

Protein function

Protein name :

Corneodesmosin

Structural protein of desmosomes in epidermis; important in skin cohesion

Expected phenotype

Skin barrier defects, epidermal abnormalities in mutant mice

Human disease relevance

Associated with skin disorders like psoriasis and hypotrichosis in humans

Model applications

Model for epidermal biology and barrier dysfunction diseases

Keywords:

Skin, Epidermis, Desmosome, Barrier function, Psoriasis

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Cdsn

conditional Knockout mouse

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