Target

Gene symbol :  
Fermt2
NCBI gene ID :  
218952
Gene full name :  
Fermitin family member 2
Synonym :  
Kind2, Mig2

Protein function

Protein name :  
Kindlin-2
Integrin-activating protein; regulates cell adhesion and signal transduction

Expected phenotype

KO causes embryonic lethality and cell adhesion defects

Human disease relevance

Implicated in fibrosis, cancer, and cardiac remodeling

Model applications

Studied in integrin signaling and tissue remodeling

Keywords:

Integrins, Adhesion, Signal transduction, Kindlin

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Fermt2

conditional Knockout mouse

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