Target

Gene symbol :  
Fgfr1op
NCBI gene ID :  
75296
Gene full name :  
FGFR1 oncogene partner
Synonym :  
FOP, FGFR1OP

Protein function

Protein name :  
FGFR1 oncogene partner protein
Centrosomal protein; involved in microtubule anchoring and ciliogenesis

Expected phenotype

Knockout mice show normal development; subtle cell cycle effects noted

Human disease relevance

FGFR1OP–FGFR1 fusions found in leukemia

Model applications

Studied in centrosome biology and fusion-driven leukemias

Keywords:

Centrosome, Microtubule, Fusion gene, Leukemia

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Fgfr1op

conditional Knockout mouse

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