Fgfr1op conditional Knockout mouse

Target

Gene symbol :

Fgfr1op

NCBI gene ID :

75296

Gene full name :

FGFR1 oncogene partner

Synonym :

FOP, FGFR1OP

Protein function

Protein name :

FGFR1 oncogene partner protein

Centrosomal protein; involved in microtubule anchoring and ciliogenesis

Expected phenotype

Knockout mice show normal development; subtle cell cycle effects noted

Human disease relevance

FGFR1OP–FGFR1 fusions found in leukemia

Model applications

Studied in centrosome biology and fusion-driven leukemias

Keywords:

Centrosome, Microtubule, Fusion gene, Leukemia

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Fgfr1op

conditional Knockout mouse

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