Target

Gene symbol :  
Hdac1
NCBI gene ID :  
433759
Gene full name :  
Histone deacetylase 1
Synonym :  
Rpd3

Protein function

Protein name :  
Histone deacetylase 1
Epigenetic regulator; removes acetyl groups from histones, modulating transcription

Expected phenotype

Embryonic lethality when knocked out; broad developmental defects

Human disease relevance

Associated with cancer, neurodevelopmental, and psychiatric disorders

Model applications

Widely used in epigenetics and cancer research

Keywords:

Epigenetics, Histone modification, Transcription, Cancer

Availability & Delivery:

  • Cryo-recovery using in-house SOPF facilities
  • Worldwide delivery by professional breeders

Hdac1

conditional Knockout mouse

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