Herc3 conditional Knockout mouse

Target

Gene symbol :

Herc3

NCBI gene ID :

73998

Gene full name :

HECT and RLD domain containing E3 ubiquitin protein ligase 3

Synonym :

KIAA1099

Protein function

Protein name :

Probable E3 ubiquitin-protein ligase HERC3

E3 ligase involved in NF-κB pathway regulation and protein turnover

Expected phenotype

Knockout mice viable; altered immune signaling noted

Human disease relevance

Linked to inflammation, cancer, and proteostasis disorders

Model applications

Used in ubiquitin signaling and immune regulation models

Keywords:

E3 ligase, NF-κB, Ubiquitin, Immunity

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Herc3

conditional Knockout mouse

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