Ltbp1 conditional Knockout mouse

Target

Gene symbol :

Ltbp1

NCBI gene ID :

268977

Gene full name :

Latent transforming growth factor beta binding protein 1

Synonym :

Ltbp-1

Protein function

Protein name :

Latent TGF-β binding protein 1

Associates with TGF-β for extracellular matrix storage and release

Expected phenotype

KO leads to craniofacial defects and vascular abnormalities

Human disease relevance

Involved in TGF-β–related pathologies including fibrosis

Model applications

Model for ECM regulation and TGF-β signaling studies

Keywords:

TGF-β, ECM, Fibrosis, Growth factor regulation

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Ltbp1

conditional Knockout mouse

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