Mks1 conditional Knockout mouse

Target

Gene symbol :

Mks1

NCBI gene ID :

380718

Gene full name :

Meckel syndrome, type 1, homolog

Synonym :

Tmem67 (paralog), Meckelin 1 (human)

Protein function

Protein name :

MKS1

Centrosomal and basal body protein required for ciliogenesis

Expected phenotype

Defects in ciliary assembly and signaling

Human disease relevance

Ciliopathies, including Meckel syndrome and Joubert syndrome

Model applications

Model for cilia formation and ciliopathy pathogenesis

Keywords:

Ciliopathy, Cilia, Centrosome, Meckel syndrome

Availability & Delivery:

Cryo-recovery using in-house SOPF facilities
Worldwide delivery by professional breeders

Mks1

conditional Knockout mouse

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